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Allergy comprehensive profile test
This test helps in the identification of antibodies to certain common inhalational agents (also called as ALLERGENS) to which your body may have a hyper immune response. Inhalational allergens are those substances which when inhaled trigger an allergic reaction in certain individuals. This test includes testing of antibodies against the 34 most common inhalational allergens.Detection of allergen specific antibodies will help in making certain lifestyle modifications and taking precautionary measures to avoid allergic response and serious consequences.
When you are exposed to these substances (allergens), immune response is over activated and there is an increased production of IgE immunoglobulin. These immunoglobulins stimulate the release of certain chemicals like histamine which cause allergic symptoms at various sites like skin, eyes, nose, digestive tract and airway. Common symptoms of allergy include the following:
Sneezing
Runny nose/stuffy nose
Itchy, watery eyes
Shortness of breath
Vomiting, loose motions
Rashes
Anaphylactic shock-severe form of allergic reaction which may even cause death
Why is allergy comprehensive profile blood test prescribed?
Your health care provider may ask you to take this test if he suspects certain periodic or persistent symptoms/diseases which are associated with allergy, like:
Itchy bumpy rashes on skin, itchy skin
Excessive sneezing/coughing
Recurrent stuffy nose/blocked nose
Throat irritation
Difficulty in breathing/recurrent pneumonia
Asthma
Eczema
Nausea, vomiting
Persistent loose motions and abdominal pain
Swelling of lips, mouth, face, tongue
Panic attack, confusion
This test also helps to monitor the response of treatment of various allergic diseases.
What are the components of allergy comprehensive profile blood test?
The list of potential allergens which are tested are:
1. Bermuda grass
2. Timothy grass
3. Johnson grass
4. Cultivated rye
5. Cultivated corn
6. Eucalyptus
7. Mesquite
8. Mugwort
9. Goosefood
10. Cocklebur
11. Rough pigweed
12. Carnation flower
13. Sunflower
14. House dust mite mix
15. Dermatophagoides farinae
16. Cockroach, German
17. Penicillium notatum
18. Cladosporium herbarum
19. Aspergillus fumigates
20. Mucor racemosus
21. Candida albicans
22. Alternaria alternata
23. Rhizopus nigricans
24. Curvularia lunata
25. Trichophyton mentagrophytes
26. Cat
27. Dog
28. Pigeon feathers
29. Chicken feathers
30. Cotton (treated)
31. Straw dust
32. Jute
33. Sheep’s wool
34. CCD marker
Procedure and prerequisites
The sample for allergy comprehensive profile test is blood, which is collected by inserting a small needle into a vein in your arm. You may feel some pain due to needle prick. No special preparations are required.
Reference range
Reference range for allergen specific IgE levels, calculated in EAST classes:
Class | Concentration (kU/l) | Result |
0 | <0.35 | No specific antibodies detected |
1 | 0.35 to <0.7 | Very low antibody titre, frequently no clinical symptoms where sensitisation is present. |
2 | 0.7 to <3.5 | Low antibody titre, existing sensitisation, frequently with clinical symptoms in the upper range of class. |
3 | 3.5 to <17.5 | Significant antibody titre, clinical symptoms usually present. |
4 | 17.5 to <50.0 | High antibody titre, almost always with clinical symptoms. |
5 | 50.0 to <100.0 | Very high antibody titre |
6 | >100.0 | Very high antibody titre |