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An arthritis panel 2 test is used to diagnose arthritis in patients. It can also be used to differentiate between different types of arthritis like rheumatoid and osteoarthritis and several autoimmune conditions. As a panel test, the arthritis panel 2 test involves using as many as eight individual tests to create a comprehensive report of the patient’s arthritis risk.
However, risk assessment is not the only goal of the arthritis panel 2 test. This test is also used by doctors to monitor disease progression in patients with any type of arthritis or it is also used to monitor treatment efficacy and condition management.
An arthritis panel 2 test is prescribed by doctors when they suspect patients to have any type of arthritis. Apart from arthritis, this panel test can also be used to rule out arthritis as a cause for the symptoms of a patient. It is also used to diagnose autoimmune conditions like Hashimoto thyroiditis or Grave’s disease in some cases. Doctors can also use this test to determine whether the cause of symptoms like joint pain, inflammation, stiffness, loss of motion range are caused by conditions like gout.
The arthritis panel 2 test has eight individual elements all of which are reported separately. The individual test elements are: CBC, CRP, ASO, Uric Acid, RA Factor, NuclearAntibody, Complement C3, Complement C4. The normal range and the possible conditions related to abnormal test results of each individual test element are mentioned below.
Complete Blood Count (CBC)
The normal range of the different elements of a CBC test are:
● White Blood Cells: 4,500 to 11,000 cells/mcL
● Red Blood Cells: 4.5 million to 5.9 million cells/mcL in men and 4.1 million to 5.9 million cells/mcL in women.
● Haemoglobin: 14 to 17.5 gm/dL in men and 12.3 to 15.3 gm/dL in women.
Any test result that’s beyond the mentioned normal range could indicate a higher risk of rheumatoid and other types of arthritis. However, the CBC test results need to be checked in context of the other tests for any definitive diagnosis.
C-Reactive Protein (CRP)
● CRP has a normal range of less than or equal to 0.5 mg/dL in both men and women.
Any report that’s higher than the mentioned normal range could indicate rheumatoid arthritis.
Antistreptolysin O Titer (ASO)
● Any ASO test result that’s less than 200 is ideal for adults (both men and women)
Abnormal ASO test results can indicate conditions like rheumatic fever or post-streptococcal reactive arthritis.
Uric Acid
● The normal range of uric acid in adult men is 3.1 to 9.2 mg/dL
● The normal range of uric acid in adult women is 2.4 to 5.7 mg/dL.
High levels of uric acid in the body can indicate gout.
Rheumatoid Factor (RA Factor)
● The RA Factor normal range is less than 14 IU/mL for both men and women
The presence of a high RA Factor in your body could indicate rheumatoid arthritis.
AntiNuclear Antibody
● Any ratio over 1:160 can be labelled as higher than normal for antinuclear antibody tests
A higher ANA ratio can indicate a higher risk of rheumatoid arthritis, systemic lupus erythematosus (SLE), or Sjögren's syndrome.
Complement C3
● The normal range of complement C3 protein in your blood is 90 to 180 mg/dL.
Higher levels of complement C3 protein in your blood could indicate rheumatoid arthritis and systemic lupus erythematosus (SLE).
Complement C4
● The normal range of complement C4 protein in your blood is 10 to 40 mg/dL.
Higher levels of complement C4 protein in your blood poses a higher risk of systemic lupus erythematosus (SLE) and rheumatoid arthritis.
The arthritis panel test is a blood test that involves drawing blood from the veins of the patient and sending it for testing. There are no prerequisites for this test, however, it is preferred if you can fast overnight before sample collection. It helps with more accurate test results