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Inflammation is one of the body's normal immune responses to any injury or infection. It can be secondary to an immune disorder or a chronic disease. Under normal conditions, the red blood cells or theerythrocytes settle slowly at the bottom of a test tube that contains a blood sample. The Erythrocyte sedimentation rate (ESR test) measures how rapidly the blood settles down in a test tube. It is a blood test that can reveal inflammatory activity in the body. It is also known as the SED rate, sedimentation rate, ESR, and Westergren sedimentation rate.
A doctor may recommend this test in the following.
To detect the cause of pain in the patients
To detect the conditions causing inflammation like vasculitis, arthritis, or inflammatory bowel disease
As a part of routine investigation
In patients suffering from Rheumatoid arthritis
In patients with cardiac or kidney disease
To detect the cause of fever
In autoimmune diseases.
This test can be done alone or as a part of a complete blood count. Conditions that cause inflammation are included in this test.RBCs, also known as erythrocytes, are used in an ESR test to gauge how rapidly they settle to the bottom of a test tube. Sedimentation, measured in millimeters per hour (mm/h), is the process by which these cells descend.
The normal range is
Women: 0 to 29 mm/hr
Men: 0 to 22 mm/hr
A Low ESR rate indicates
Cardiac disease
Liver problem
RBC disorders
Kidney disease
A high ESR indicates
Anemia
Kidney disease
Cancer
Tissue injury
Arthritis
Infections
A blood sample is taken from the vein,
No special test preparation is required for an ESR test.
Before the test, the doctor must know about any drugs or supplements that one is taking
The RBCs in the test tube are monitored for one hour to determine the ESR.
The report comes within a few hours of the test.
Some doctors recommend fasting before the test
The test is not diagnostic but, of course, is an indication of underlying pathology which needs to be further evaluated